Is parapsoriasis a cancer?
Small-plaque parapsoriasis is usually noncancerous (benign). However, extremely rarely, small-plaque parapsoriasis turns into cutaneous T-cell lymphoma (CTCL), which is a type of skin cancer that is caused by specific types of white blood cells called lymphocytes.
What causes small plaque Parapsoriasis?
Doctors may also call this condition parapsoriasis en plaques or Brocq’s disease. Parapsoriasis may look like psoriasis, but its underlying cause is a disorder in immune system cells called T cells that are located in the skin.
How do I get rid of psoriasis permanently?
There’s no cure for psoriasis. But treatment can help you feel better. You may need topical, oral, or body-wide (systemic) treatments. Even if you have severe psoriasis, there are good ways to manage your flare-ups.
Does having psoriasis shorten your life?
Some studies have suggested that patients with the more severe forms of psoriasis have a significantly reduced life expectancy due to the fact that they are more likely to suffer from comorbidities including cardiovascular disease and diabetes.
What is the difference between LPP and small plaque parapsoriasis?
There are two types of parapsoriasis; small plaque parapsoriasis (SPP) and large plaque parapsoriasis (LPP). Out of the two types, LPP is considered a premalignant dermatosis with a risk of progressing to mycosis fungoides or cutaneous T-cell lymphoma, while SPP is a chronic benign condition.
Is there a cure for large plaque parapsoriasis?
Large plaque parapsoriasis has an irregularly shaped, well-demarcated, and sometimes wrinkled appearance, which in about 10% of cases evolves into mycosis fungoides. Skin biopsies are nondiagnostic and treatment with UV light is usually successful.
How can I find out more about parapsoriasis?
Visit the website to explore the biology of this condition. PubMed is a searchable database of medical literature and lists journal articles that discuss Parapsoriasis. Click on the link to view a sample search on this topic. Questions sent to GARD may be posted here if the information could be helpful to others.
How is PCR used to treat parapsoriasis?
Clonal rearrangement of T cell receptor done by polymerase chain reaction (PCR) is found in lesional skin in variable percentages of both types of parapsoriaisis, although more frequently in LPP. There are no published recommendations for immunohistochemical and genotypic analysis in parapsoriasis.