Categories :

What is anti-HBe positive mean?

What is anti-HBe positive mean?

Positive anti-HBe results usually indicate inactivity of the virus and low infectivity. Positive anti-HBe results in the presence of detectable HBV DNA in serum also indicate active viral replication in these patients.

What is anti-HBe AB?

Anti-HBe are one of the antibodies produced by the body when it defends itself against hepatitis B. These antibodies are directed against the “soluble” or extractable part of the “core” antigen of the hepatitis B virus (HBV).

What is the normal range of anti HBe?

Any value between 1 and 5 s/c is indeterminate and should be repeated. For hepatitis B surface antibody (anti-HBs), a level less than 5 mIU is considered negative, while a level more than 12 mIU is considered protective. Any value between 5 and 12 mIU is indeterminate and should be repeated.

What is IgG anti HBe?

Anti-HBc (IgG and IgM) antibodies are the body’s first response to a hepatitis B virus (HBV) infection. These antibodies are directed against a portion of the HBV called the core. Anti-HBc IgG and IgM appear shortly after the symptoms and onset of the virus surface antigen (HBsAg).

Can HBsAg positive become negative?

Your test results may not mean you have a problem. Ask your healthcare provider what your test results mean for you. Normal results are negative or nonreactive, meaning that no hepatitis B surface antigen was found. If your test is positive or reactive, it may mean you are actively infected with HBV.

What is non-reactive HCV?

What does a non-reactive HCV antibody test result mean? ► A non-reactive or negative antibody test means that you are not currently infected with the hepatitis C virus. ► However, if you think you might have been exposed to hepatitis C in the last 6 months, you will need to be tested again.

What is the normal range of HBV viral load?

HBV: Hepatitis B virus. # Normal values: ALT: Males: 10-40 U/L; Females: 7 – 35 U/L; AST: Males: 15 – 40 U/L; Females: 13 – 35 U/L. HBeAg-positive patients had significantly higher ALT levels (mean 170.3 ± 391 IU/L) compared to HBeAg-negative patients (mean 53.9 ± 169.4 IU/L), p < 0.0001 (Table 2).

Can HBsAg positive be cured?

Most adults with hepatitis B recover fully, even if their signs and symptoms are severe. Infants and children are more likely to develop a chronic (long-lasting) hepatitis B infection. A vaccine can prevent hepatitis B, but there’s no cure if you have the condition.

What is normal range of anti HCV?

Normal range for this assay is “Not Detected”. The quantitative range of this assay is 10 – 100,000,000 IU/mL (1.0 – 8.0 log IU/mL).

What is the normal range of HCV viral load?

Understanding the viral load range The viral load results from the quantitative PCR test can range from 15 to 100,000,000 IU/L. If your results are: Fewer than 15 IU/mL: The virus is detected, but the amount can’t be measured exactly. You may need to return later for another test to see if the measurement changes.

What is a good viral load count?

A high viral load is generally considered about 100,000 copies, but you could have 1 million or more. The virus is at work making copies of itself, and the disease may progress quickly. A lower HIV viral load is below 10,000 copies.

What does a positive anti HBe antibody mean?

In hepatitis B virus (HBV) carriers and in patients with chronic hepatitis B, positive anti-HBe results usually indicate inactivity of the virus and low infectivity of the patients. Positive anti-HBe results in the presence of detectable HBV DNA in serum indicate active viral replication.

Can a HBE positive patient be an HBE negative patient?

Anti-HBe-positive patients in the reactivated phase of the disease are also referred to as the HBeAg-negative viremic group. Genomic analyses has revealed that such patients carry natural mutants of the virus that have either reduced levels (core promoter variants) or complete abrogation of HBeAg (precore variants) production.

Can a HBV positive subject be an anti HBc positive?

Evaluation of anti-HBc positive subjects in HBV endemic region. Those subjects who are seronegative for both HBsAg and anti-HBs, that is, isolated anti-HBc positivity, could be further classified into three categories.

When to use a reactive or non-reactive anti-HBe?

REACTIVE: A REACTIVE anti-HBe indicates early convalescence when HBeAg has declined below detectable levels. NON-REACTIVE: A NON-REACTIVE result may indicate early acute infection before the peak of viral replication. See Special Instructions for PHL recommended diagnostic approach to hepatitis. Clinical Reference